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Item #10130

AO ProToothpaste

Antioxidant toothpaste with naturally sourced ingredients. Fluoride free.
3 ounces


AO ProToothpaste/Natural provides maximum cleaning power without harsh chemicals. Natural and plant-based cleaning and polishing agents gently remove stains and thoroughly clean while removing unhealthy build-up with brushing. Antioxidants phloretin and ferulic acid work synergistically with catechins from green tea for maximum antioxidant effect on teeth. Free of alcohol, fluoride, sodium lauryl sulfate, parabens, and artificial sweeteners; contains seabuckthorn oil and perilla seed extract.

For best results, use with AO ProRinse/Natural and AO ProVantage Antioxidant Gel.


Antioxidant Ingredients

Combination antioxidants have been shown to act in concert and have a strong synergistic effect compared to single antioxidants.
Phloretin is a polyphenolic compound in the sub-group flavonoids and is mainly derived from apples. It is a potent antioxidant and has been shown to inhibit several types of destructive enzymes. Phloretin is known to adsorb to lipid surfaces, such as cell membranes.
Ferulic Acid
This effective, polyphenolic antioxidant is a substance found in the seeds and leaves of most plants, especially in the brans of grasses such as wheat, rice and oats. Its chemical structure strongly resembles that of curcumin, also a potent polyphenol. Polyphenols are so named because they have multiple phenolic constituents.
Epigallocatechin Gallate (EGCG)
Green tea polyphenols comprise four catechins of which EGCG is the dominant and most potent one. One branch of research focused on oral health applications associated with EGCG and showed that it is able to quickly act against odor-causing volatile sulfur compounds, and also that it can carry out a preventative function with regards to plaque and caries formation and the development of gingivitis.

Other Ingredients

Menthol Peppermint Oil
Menthol is a purified compound from peppermint oil. Menthol is responsible for imparting a cooling, soothing effect; a property present in whole peppermint oil, but multiplied in pure menthol. In addition to this flavoring ability, for which it is mostly used, peppermint oil has excellent antibacterial and antifungal properties. In a study published in Mycopathologica in 2008, the inhibitory effect of 30 plant oils including peppermint was evaluated against biofilm forming Candida albicans strain (CA I) isolated from clinical samples. Peppermint oil showed 74.16% biofilm reduction.
Perilla Ocymoides Extract
Perilla is an herb widely grown in Asia with many applications. Perilla leaf and seed extracts are rich in polyphenols, particularly luteolin and apigenin. The extract exhibits strong superoxide scavenging ability, likely the reason for its anti- inflammatory potential. Perilla extract was tested specifically for application in the oral cavity and was shown to inhibit cariogenic and periodontopathogenic bacteria.
Hippophae Rhamnoides (Seabuckthorn)
Seabuckthorn belongs to the Elaeagnaceaea (Oleaster) family and is common in Europe and Asia. Its fruit is a bright orange berry about one third the size of a blueberry. The seabuckthorn berry is rich in antioxidants, essential omega fatty acids, has twelve times the Vitamin-C of an orange and contains more than 190 bioactive nutrients.
Chamomile is a member of Asteraceae/Compositae family and is represented by two varieties: German Chamomile (Chamomilla recutita) and Roman Chamomile (Chaemaemelum nobile). The dried flowers of chamomile are rich in flavonoids contributing to its medicinal properties. Alpha-bisabolol, one of the known constituents of chamomile is known to impart a soothing effect when used topically.
Over half the dry weight of human bone, 97% of dental enamel and 70% of dentine is comprised of hydroxyapatite. Natural and synthetic hydroxyapatite have a strong affinity with the human body, and are used widely in orthopedic and dental applications. Within the realm of dental research, hydroxyapatite was shown to improve tooth color, likely due to its ability to adsorb cariogenic bacteria and to remineralize subsurface areas that have been demineralized. A study conducted at the University of Indiana concluded that a paste containing hydroxyapatite reduced the number of days of dental sensitivity following bleaching. Hydroxyapatite, combined with hydrated silica, achieves superior cleaning that will keep teeth bright.
This stain-lifting polymer was tested intensively and shown to lift stains by complexing with compounds that cause discoloration. A series of in vitro studies on HAP disks showed that pastes and rinses with Plasdone achieved results superior to products without it, both with regards to overall brightenss and removal of stains from tea, coffee and red wine. Plasdone is a non-oxidative, non-peroxide and non-abrasive ingredient.


Adults and children 2 years of age and older:

Adults and children 2 years of age and older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or doctor. Instruct children under 6 years of age in good brushing and rinsing habits (to minimize swallowing). Supervise children as necessary until capable of using without supervision.

Children under 2 years of age:

Ask your dentist or physician.


AO ProVantage Gel

Antioxidant infused dental gel, AO ProVantage will soothe and improve the appearance of soft tissue in the oral cavity.

30 ml bottle


AO ProRinse

Antioxidant oral rinse to freshen breath and bathe tissues with powerful natural ingredients. Alcohol free.

10 fluid ounces


AO ProRinse

** Backordered **

Antioxidant oral rinse to freshen breath and bathe tissues with powerful natural ingredients. Alcohol free.

32 fluid ounces


Antioxidant Oral Care System

PerioSciences complete oral care systems redefine oral care. The family of AO Pro products utilize novel combinations of specific antioxidants for any oral care concern. Stand sold separately.

60 day supply


Worried about ingredients in your oral care products known to cause irritation and drying?

Learn About Hydrating »


Do you have sensitive places on your teeth?

Learn About Sensitive »

White Care

Do you professionally whiten your teeth or use teeth strips?

Learn About White Care »


Do you want an all natural alternate to traditional toothpaste?

Learn About Natural »

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